Best Formulations (Sirio Americas)
City of Industry, California
Profile updated: March 12, 2026
Best Formulations has manufactured dietary supplements and softgels from City of Industry, California since 1984. The company was acquired by Sirio Pharma in 2023 and now operates as Sirio Americas. This gives them access to a global network spanning Asia and Europe. Best Formulations is one of the largest plant-based softgel manufacturers in the United States. They specialize in difficult paste-style softgel formulas and probiotic handling. The company holds an FDA drug license, which is a higher regulatory standard than standard dietary supplement registration. Their four Southern California facilities total over 120,000 sq ft. They also report NPA GMP certification and NSF GMP for Sport designation, making them suitable for sports nutrition brands. The Sirio acquisition brings institutional-grade resources but may add corporate complexity for smaller brands.
Min. Order
Not publicly disclosed
Lead Time
Not publicly disclosed
Product Types
Softgels, Tablets, Capsules, Powders, Gummies, Liquids
Capabilities
Contract Manufacturing, Custom Formulation, Plant-Based Softgels, Probiotic Handling, R&D
Dosage Forms
Certifications
1 of 5 certifications independently confirmed. What this means
Key Regulatory Concepts
Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.
Review Notes
NSF GMP for Sport designation independently confirmed via NSF 306 Section 6 directory (2026-03-28). NPA GMP certification is self-reported and not found in NPA public directory (parent Sirio Pharma is listed). All other certifications (FDA Drug License, cGMP, FDA Registration) are self-reported. The 2023 acquisition by Sirio Pharma (Shenzhen-listed, 300791.SZ) introduces a question that matters to brands evaluating long-term partnerships: how much operational independence does the U.S. facility retain?
Sources
- Best Formulations - Official Website(2026-03-12)
- NSF GMP for Sport Designation (New Hope)(2026-03-12)
- Sirio Pharma Acquisition (Nutritional Outlook)(2026-03-12)
- NSF International GMP Directory(2026-03-18)
Disclosures
- No material connection exists between Inventory Ready and this manufacturer
- Best Formulations is a subsidiary of Sirio Pharma Co., Ltd. (publicly traded: 300791.SZ)
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