JBSL-USA (Japan Bio Science Laboratory)
JBSL-USA is the US office of Japan Bio Science Laboratory (JBSL), founded in 1974 and headquartered in Osaka, Japan. JBSL is the pioneer of nattokinase research and in 1998 was the first company in the world to isolate and market this unique fibrinolytic enzyme. Their flagship ingredient, NSK-SD nattokinase, is fermented using JBSL's patented strain of Bacillus subtilis natto and is the only nattokinase with published identity, safety, and efficacy studies. NSK-SD has self-affirmed GRAS status in the US and novel food approval in Europe. The ingredient is supported by 50+ published studies including 30+ human clinical trials demonstrating cardiovascular and circulatory health benefits.
Walnut Creek, California
Directory Listing · Records Reviewed
Public records and independent sources have been reviewed.
What this means →- MOQMOQ (Minimum Order Quantity)The smallest production run a manufacturer will accept for an order.
- Not publicly disclosed
- LEAD TIMELead TimeThe time from order placement to finished product delivery.
- Not publicly disclosed
§1Editorial assessment
JBSL-USA is the US office of Japan Bio Science Laboratory (JBSL), founded in 1974 and headquartered in Osaka, Japan. JBSL is the pioneer of nattokinase research and in 1998 was the first company in the world to isolate and market this unique fibrinolytic enzyme. Their flagship ingredient, NSK-SD nattokinase, is fermented using JBSL's patented strain of Bacillus subtilis natto and is the only nattokinase with published identity, safety, and efficacy studies. NSK-SD has self-affirmed GRAS status in the US and novel food approval in Europe. The ingredient is supported by 50+ published studies including 30+ human clinical trials demonstrating cardiovascular and circulatory health benefits.
§2Our review
The six checks in our review, applied before any name appears in the directory. Each check is auto-derived from public evidence on this profile.
§3Inspection history
§4Certifications
Certification verification in progress. International supplier records require regional database lookups (EudraGMDP, Health Canada NHP, FSSC public register, JHFA directory). See our methodology.
§5Capability matrix
- PRODUCT TYPES
- NSK-SD Nattokinase (Fibrinolytic Enzyme) · Patented Bacillus subtilis natto Fermentation
- CAPABILITIES
- Nattokinase Pioneer (First to Market, 1998) · Patented Bacillus subtilis natto Fermentation · Branded Ingredient Supply (NSK-SD) · Self-Affirmed GRAS (US) · EU Novel Food Approved · Clinical Research Programs (50+ Studies, 30+ Human Trials)
§6Sources
- JBSL-USA Official Website — About(2026-04-02)
- Nutraceuticals World — JBSL Japan Celebrates 50th Anniversary(2026-04-02)
Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.
Disclosures
- No material connection exists between Inventory Ready and this company
For the check-by-check breakdown that produces this vendor's score, see our scoring framework. The connection map between JBSL-USA (Japan Bio Science Laboratory) and other vendors, capabilities, and certifications is in the manufacturer atlas.
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