Aphena Pharma Solutions
Aphena Pharma Solutions is a large-scale contract packaging and manufacturing company based in Cookeville, Tennessee. The company completed a $20 million expansion adding a purpose-built 500,000-square-foot facility for pharmaceutical and dietary supplement packaging. Aphena's Tennessee campus totals 578,000 square feet of solid and semi-solid dose packaging capacity. The company meets and exceeds FDA standards for 21 CFR Parts 111, 210, 211, and 820, and is DEA (CII-V) licensed, ISO 13485:2016 and ISO 9001:2015 certified (BSI), and UL Certified. Secondary packaging services include PDQ display assembly, kitting, cartoning, blister packaging (cold-form and thermoform), shrink wrapping, rework, and serialization. Aphena also operates a 3PL division centrally located within a day's drive of 75% of the US population. The company has a ThomasNet profile and is covered in Healthcare Packaging magazine.
Cookeville, Tennessee
Directory Listing · Records Reviewed
Public records and independent sources have been reviewed.
What this means →- MOQMOQ (Minimum Order Quantity)The smallest production run a manufacturer will accept for an order.
- Not publicly disclosed
- LEAD TIMELead TimeThe time from order placement to finished product delivery.
- Not publicly disclosed
§1Editorial assessment
Aphena Pharma Solutions is a large-scale contract packaging and manufacturing company based in Cookeville, Tennessee. The company completed a $20 million expansion adding a purpose-built 500,000-square-foot facility for pharmaceutical and dietary supplement packaging. Aphena's Tennessee campus totals 578,000 square feet of solid and semi-solid dose packaging capacity. The company meets and exceeds FDA standards for 21 CFR Parts 111, 210, 211, and 820, and is DEA (CII-V) licensed, ISO 13485:2016 and ISO 9001:2015 certified (BSI), and UL Certified. Secondary packaging services include PDQ display assembly, kitting, cartoning, blister packaging (cold-form and thermoform), shrink wrapping, rework, and serialization. Aphena also operates a 3PL division centrally located within a day's drive of 75% of the US population. The company has a ThomasNet profile and is covered in Healthcare Packaging magazine.
§2Our review
The six checks in our review, applied before any name appears in the directory. Each check is auto-derived from public evidence on this profile.
§3Inspection history
§4Certifications
0 of 6 certifications independently confirmed. What this means
§5Capability matrix
- PRODUCT TYPES
- Secondary Packaging · Blister Packaging · Cartoning · Kitting and Assembly · PDQ Display Assembly · Serialization
- CAPABILITIES
- 578,000 sqft Packaging Campus · Primary and Secondary Packaging · PDQ Display Assembly · Blister Packaging (Cold-Form + Thermoform) · Kitting and Rework · Cartoning and Serialization · 3PL Division (75% US in 1 Day) · DEA Licensed (CII-V)
§6Sources
- Aphena Pharma - Secondary Packaging(2026-03-26)
- ThomasNet - Aphena Pharma Solutions Profile(2026-03-26)
- Healthcare Packaging - Aphena $20M Expansion Complete(2026-03-26)
Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.
What We Couldn't Verify
- On-site facility inspection was not conducted
- Primarily pharmaceutical-focused; dietary supplements are one vertical
- All certifications are self-reported
- Large-scale operation may not serve very small supplement startups
Last reviewed: March 26, 2026
Disclosures
- No material connection exists between Inventory Ready and this company
For the check-by-check breakdown that produces this vendor's score, see our scoring framework. The connection map between Aphena Pharma Solutions and other vendors, capabilities, and certifications is in the manufacturer atlas.
Our Evaluation Method
Every manufacturer assessment follows six principles:
- Evidence: Claims backed by documentation, not marketing copy
- Freshness: Information reviewed and dated within the last 12 months
- Provenance: Sources cited for every key claim
- Challenge: Inconsistencies flagged, not hidden
- Disclosure: Material connections stated directly on affected listings
- Abstention: When we can't assess, we say so explicitly
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